LINKS & REFERENCE
For your reference


   
Actual blood flow is not always consistent with what is indicated on the machine blood pump display setting. The greater the negative arterial pressure, the greater the “negative” effect on the actual delivered blood flow. Multiple factors contribute to increased negative pressure, however poor access flow is most common cause.
 

 
-240mm / Hg is the upper limit of negative pre pump arterial pressure accepted in clinical practice. Even with negative arterial pressure within allowable limits, there is already a 9% reduction in actual blood flow. The best way to prevent further reductions in delivered blood flow is to monitor arterial pressure.
 

 
If actual blood flow delivered is less than expected, clearances will be negatively affected.
 

 

Larger needles such as 15 gauge size are indicated for blood flow rates in excess of 400ml / minute to help prevent the occurrence of high negative arterial pressure – thus helping to ensure that adequate blood flow rates are achieved.

Smaller size needles used in conjunction with high blood flow rates result in higher negative arterial pressure.

 

 
This graph indicates that as blood flow rates are increased with the use of smaller bore needles, the negative pre-pump arterial pressure increases. This has a negative effect on the delivered blood flow.